1. HBOT increases Stem
Cell Growth:
According to a study to
be published in the American Journal of Physiology-Heart and Circulation
Physiology, a typical course of hyperbaric oxygen treatments increases by
eight-fold the number of stem cells circulating in a patient’s body. Stem
cells, also called progenitor cells are crucial to injury repair.
Stem cells exist in the
bone marrow of human beings and animals and are capable of changing their
nature to become part of many different organs and tissues. In response to
injury, these cells move from the bone marrow to the injured sites, where they
differentiate into cells that assist in the healing process.
The movement, or mobilization,
of stem cells can be triggered by a variety of stimuli — including
pharmaceutical agents and hyperbaric oxygen treatments. Where as drugs are
associated with a host of side effects, hyperbaric oxygen treatments carry a
significantly lower risk of such effects.
2. HBOT significantly
reduces swelling:
Dilation or blood vessel
widening following damage to tissue results in decreased blood flow. That
increase in blood flow couples with revascular permeability (movement of fluid
in and out of blood vessels) to increase protein and fluids outside blood
vessels reducing tissue swelling. HBOT significantly reduces swelling, and
reduces the pain associated with it.
As the oxygen supply reduces,
blood flow increases which will only serve to exacerbate the swelling and
impede the inflammatory process that assists the commencement of healing.
3. HBOT significantly
reduces Edema (Swelling)
The development of edema
(swelling) is caused by a number of factors such as an increase in local blood
flow and also damage to local blood and lymphatic vessels.
The pressure exerted by
edema on surrounding structures can compromise circulation. When this pressure
approaches or exceeds that in the blood vessels, then blood flow will slow or
cease altogether.
Swelling also contributes
to tissue hypoxia (a shortage of oxygen in the tissues) by increasing the
distance between the capillary (smallest blood vessels) and the cells, which
impedes cell function, metabolism and the inflammatory process by increasing
the diffusion distance (movement of particles from an area of high
concentration to an area of low concentration).
Hyperbaric oxygen therapy is
able to combat the increased distance for oxygen diffusion from blood vessel to
cells by increasing the oxygen content within the blood which will result in an
increased oxygen delivery to cells and tissues, shortening the inflammatory
process, thereby speeding the healing and repair of tissues.
4. HBOT significantly
shortens the inflammatory process:
The bodies initial
response to any injury involves inflammation. Inflammation is the process by
which cells such as phagocytes (white blood cells) gain access to the
damaged/injured tissues to prevent infection and enable healing to commence.
Decreased oxygen supply greatly impacts the inflammatory process as the cells
involved in inflammation are oxygen dependent. Should oxygen supply be
decreased, the inflammatory process and healing will be impaired.
Increased oxygen availability
promotes vasoconstriction when blood vessels in the body become smaller which
causes fluid reabsorption and helps reduce edema while keeping the tissue well
oxygenated. This supports the cells of the inflammatory process in removing
cell debris and micro-organisms that impede infection. White blood cells have
an increase in cellular energy that speeds up their activity and reduces the
time of the inflammatory process.
5. HBOT improves range of
motion:
Following hyperbaric
oxygen therapy, swelling is also decreased and resolved more rapidly. As a
result, pain will be less allowing for the return of range of motion as the
healing process gains momentum and inflammation is decreased.
6. HBOT increases the
production of collagen:
Following the initial
healing process of the inflammatory response and the prevention or removal of
infection, comes the next chapter in tissue/wound healing.
Collagen is the
connective tissue developed and laid down by fibroblasts, the repair cells of
the body. Collagen acts as a base layer in the healing wound and assists the
wound to close and repair. The formation of collagen and hence wound
healing/recovery is highly dependent on the presence of adequate amounts of
oxygen. The actual production of collagen by fibroblasts is also extremely
dependent on oxygen availability.
As hyperbaric oxygen therapy
markedly increases the oxygen available within the blood this in turn enables
for a cross-linking or strengthening of the tissues, and fibroblasts to produce
increased amounts of collagen required for healing of wounds and tissue damage.
7. HBOT increases growth
of cells that form reparative tissue (Fibroblastic proliferation)
Clinical research has
demonstrated that a number of days following injury there occurs a migration of
fibroblasts (connective tissue cells responsible for collagen production) into
the area of damage. These cells then divide and replicate producing large
amounts of collagen (connective tissue used to repair damage to tissue) that
acts as the building block for the healing of tissue and wounds.
The development and migration
of fibroblasts is assisted by the influx of oxygen resulting from hyperbaric
oxygen therapy, this then supports the development and action of these
particular cells which play a vital part in the healing/recovery process.
8. HBOT supports scar
tissue rehabilitation:
A decrease in oxygen
available to cells such as fibroblasts impairs their action, impacting upon the
healing of tissue, causing healing to take longer, and inhibiting the quality
of scar tissue developed or rehabilitated, which in turn greatly decreases
tissue strength.
Healing occurs both faster and
stronger in wounds/injuries that are treated with hyperbaric oxygen therapy due
to the demands of oxygen availability by the cells and tissues responsible for
the healing process being met.
9. HBOT promotes greater
tissue strength:
As the oxygen
concentration of the blood increases during hyperbaric oxygen therapy, cells
further from blood vessels are more adequately oxygenated. Hyperbaric oxygen
therapy allows for increased oxygen availability in more extensive areas
enabling fibroblasts to carry out their part of the healing process for tissue
damage and injury, more rapidly covering larger areas.
Hyperbaric oxygen therapy
saturates the blood plasma with oxygen, this in turn reaches the areas of
damage/injury with greater efficiency than red blood cells, providing all cells
and tissues with the much needed agent for healing, oxygen. The cells
responsible for the development of scar tissue for healing are then able to
carry this out more rapidly and the resulting tissue integrity is
stronger.
10. HBOT enhances the
growth of new blood vessels (Angiogenesis)
Injury or damage to
tissues also results in damage and destruction of the supporting blood vessel
structures. The healing process is reliant on these structures for supply of
the blood containing the cells and nutrients that carry out and enable healing
as well as the removal of damaged cells, debris and foreign micro-organisms.
Research has demonstrated that
treatment with hyperbaric oxygen therapy significantly increases the number and
actual size of blood vessels in damaged tissues and wounds. This allows the
healing process to occur faster speeding the recovery of the injury or
wound.
11. HBOT increases oxygen
levels in tissues (Hyperoxia)
With an increase in
oxygen availability resulting from both blood that is highly saturated in
oxygen dissolved in the plasma, and an increase in the number of blood vessels
due to new vessels being created as well as the healing of damaged blood
vessels, tissues and cells become highly saturated in oxygen.
12. HBOT increases oxygen
perfusion area around wounds:
Oxygen perfusion around
wounds and damaged tissues is greatly increased when the blood supply to these
areas possesses greater than normal levels of oxygen within blood plasma as
well as carried on red blood cells. The oxygen contained in the blood plasma is
more easily accessible than that carried to the tissues and cells of the wound/damaged
area on red blood cells, and this method of oxygen supply is less labour
intensive and energy taxing.
The cells involved in the
healing process are highly dependent on oxygen to carry out their healing
function and this increased demand for oxygen in the area around wounds by the
increased number of healing cells in that location is met by the increased
oxygen saturation of the blood following hyperbaric oxygen therapy.
13. HBOT stimulates new
capillary growth:
During the time of injury
and damage the microcirculation and the blood vessels of this circulation
(capillaries) are vital to the healing process through the supply of nutrients
and oxygen and the removal of waste and debris to enable the cells responsible
for healing to successfully complete their function.
Growth of new, and repair of
damaged capillaries are stimulated within the damaged tissues by hyperbaric
oxygen therapy, providing increased oxygen availability to these areas. The
increased oxygen supply and increased pressure employed by hyperbaric oxygen
supply are both responsible for the stimulation of new capillary growth and the
repair of existing capillaries.
14. HBOT improves the
survival of tissues in the ‘grey area’ of crush injuries:
The ‘grey area’ of crush
injuries can be defined as the area between the tissues that are obviously
irreversibly damaged and those tissues that are undamaged. The tissues of the
‘grey area’ benefit greatly from increased oxygen supply, improved circulation
and blood supply. These are the aspects that will allow the tissues of the
‘grey area’ to be saved, salvaged and repaired.
Hyperbaric oxygen therapy has
been shown to support and maintain tissue oxygenation within the ‘grey area’
resulting in a better outcome for the tissues, wound or injury.
15. HBOT increases
production and improves the action of Osteoblasts and Osteoclasts
Osteoblasts are the cells
responsible for bone formation and osteoclasts are the cells responsible for
bone reabsorption. Both these cells work together to form bones and control the
amount of bone tissue.
The provision of increased
levels of oxygen allows for increased production of these cells and enables
them to conduct bone repair and formation more adequately through the reduction
of oedema and growth of new blood vessels in the micro-circulation.
16. HBOT improves bone
regeneration for faster recovery:
When the inflammatory
process, swelling and oedema is rectified more rapidly the repair and
regeneration of bone is able to commence sooner.
With the increase in blood
supply and oxygen availability, the tissues and cells responsible for bone
regeneration are able to carry out their task of healing more efficiently,
resulting in accelerated recovery and a better result in the healing tissues.
17. HBOT helps prevent
infection:
Research has demonstrated
that having lower oxygen levels in tissues and wounds increases the possibility
of infection. Changes in wound and tissue oxygenation impacts greatly upon the
wound immune mechanism.
Having an improved or increased
tissue oxygen supply reduces the incidence of wound infection as the cells
responsible for prevention and recovery from infection are dependent on oxygen,
therefore additional oxygen benefits the healing process.
18. HBOT increases white blood
cell production:
The major players in the
bodies immune response are the white blood cells. Providing the body with
increased oxygen availability increases the production of white blood cells
providing benefit to the bodies immune response.
High-dose oxygen delivered
under pressures greater than sea level (hyperbaric oxygen therapy), stimulates
and enables the bodies immune response
19. HBOT enhances ability
of white blood cells to remove bacteria and debris (Leukocyte activity):
Without oxygen or in a
hypoxic (shortage of oxygen in the body) environment the function of white
blood cells becomes diminished. This in turn provides a significant threat of
infection as the bodies immune response is impaired.
The increased oxygen supply
offered by hyperbaric oxygen therapy assists in bacterial killing through
improving leukocyte (type of white blood cell) function.
20. HBOT potentiates the
use of antibiotics:
Research has demonstrated that periods of hyperoxia (increased
oxygen levels in tissues) and hyperbaric oxygen therapy has influenced the
activity of some antibiotics, enhancing their effectiveness. This enables the
presenting infection to resolve quicker.
21. HBOT destroys harmful
bacteria (Antimicrobial effect):
Hyperbaric oxygen therapy
provides direct bactericidal (substance that kills bacteria) and bacteriostatic
(hampers the growth of bacteria) effects against bacteria due to the generation
of oxygen free radicals. These free radicals are able to damage the membranes
and make up of the bacteria rendering them ineffective or killing them.
Anaerobic (without oxygen)
organisms find an increased oxygen environment toxic and are unable to survive.
22. Hyperbaric
Oxygenation Effects the Blood Flow:
Normal blood flow: There
is 21% oxygen in the air that we breathe, and our lungs transfer this oxygen to
our red blood cells (via hemoglobin). These oxygen-filled red blood cells are
carried around the body by the plasma (fluid), which travels through the blood
vessels. The oxygen diffuses into the surrounding tissue ensuring that it is
delivered to where it is needed most.
Ask us for more info:
Bird Medical Devices, Mumbai, India.
Tel:91-22-65655123 Mobile: 91-9769 484 123 (or) 91-9769 006 123
Email: info@indiahbot.com (or) indiahbot@gmail.com
(The content and information provided within this site is for informational and educational purposes only. The information provided within this site is not to be considered as a medical advice.)
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